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LabMedMolGe - Team

Giovanna Marchese

Giovanna Marchese

e-mail:gmarchese@unisa.it

 

Academic degree in Biology cum laude, Calabria University  (2006)

 

Italian National Habilitation Degree as ProfessionalBiologist, Calabria University (2007)

 

PhD in Molecular Medicine, Siena University (2011)

 

Master in Innovations Research in Health Sciences; Genomics and Bioinformatics educational path, University of Salerno (2014)

Co-founder of the university spin-off and innovative start-up Genomix4Life S.r.l. (www.genomix4life.com)

 

Expertise and research activities: genomics, molecular and cellular biology. Microarrays mRNA and miRNA expression profiling; Massively parallel sequencing applications; SNPs Genotyping

 

 Publications:

  • Cannarella R, Salemi M, Condorelli RA, Cimino L, Giurato G, Marchese G, Cordella A, Romano C, La Vignera S, Calogero AE. SOX13 gene downregulation in peripheral blood mononuclear cells of patients with Klinefelter syndrome. Asian J Androl. 2020 Oct 27. doi: 10.4103/aja.aja_37_20. Epub ahead of print. PMID: 33109779.
  • Pierri L, Saggese P, Guercio Nuzio S, Troisi J, Di Stasi M, Poeta M, Savastano R, Marchese G, Tarallo R, Massa G, Ciccone V, Ziegenhardt D, Cavallo P, Bergheim I, Weisz A, Vajro P. Relations of gut liver axis components and gut microbiota in obese children with fatty liver: A pilot study. Clin Res Hepatol Gastroenterol. 2018 Sep;42(4):387-390. doi: 10.1016/j.clinre.2018.03.015. Epub 2018 Jul 10. PMID: 29773420.
  • Cimino L, Salemi M, Cannarella R, Condorelli RA, Giurato G, Marchese G, La Vignera S, Calogero AE. Decreased miRNA expression in Klinefelter syndrome. Sci Rep. 2017 Nov 30;7(1):16672. doi: 10.1038/s41598-017-16892-3. PMID: 29192217; PMCID: PMC5709391.
  • Tarallo R, Giurato G, Bruno G, Ravo M, Rizzo F, Salvati A, Ricciardi L, Marchese G, Cordella A, Rocco T, Gigantino V, Pierri B, Cimmino G, Milanesi L, Ambrosino C, Nyman TA, Nassa G, Weisz A. The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Genome Biol. 2017 Oct 6;18(1):189. doi: 10.1186/s13059-017-1321-0. PubMed PMID: 29017520.
  • Rizzo F, Rinaldi A, Marchese G, Coviello E, Sellitto A, Cordella A, Giurato G,Nassa G, Ravo M, Tarallo R, Milanesi L, Destro A, Torzilli G, Roncalli M, Di Tommaso L, Weisz A. Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma. Oncotarget. 2016 Aug 23;7(34):54650-54661. doi: 10.18632/oncotarget.10567.
  • Marchese G, Rizzo F, Guacci A, Weisz A, Coppola G. Kleefstra-variant syndrome with heterozygous mutations in EHMT1 and KCNQ2 genes: a case report. Neurol Sci. 2016 May;37(5):829-31. doi: 10.1007/s10072-016-2482-4.
  • Rizzo F, Ambrosino P, Guacci A, Chetta M, Marchese G, Rocco T, Soldovieri MV, Manocchio L, Mosca I, Casara G, Vecchi M, Taglialatela M, Coppola G, Weisz A. Characterization of two de novoKCNT1 mutations in children with malignant migrating partial seizures in infancy. Mol Cell Neurosci. 2016 Apr;72:54-63. doi:10.1016/j.mcn.2016.01.004.
  • Guacci A, Chetta M, Rizzo F, Marchese G, De Filippo MR, Giurato G, Nassa G, Ravo M, Tarallo R, Rocco T, Operto FF, Weisz A, Coppola G. Phenytoin neurotoxicity in a child carrying new STXBP1 and CYP2C9 gene mutations. Seizure. 2016 Jan;34:26-8. doi: 10.1016/j.seizure.2015.11.004.
  • Chetta M, Guacci A, Rizzo F, Marchese G, Operto FF, Weisz A, and Coppola G.  Infantile spasms in early-onset Niemann-Pick disease with a novel compound heterozygous mutations in SMPD1 gene. New Horizons in Translational Medicine. 2015 Sep; 2(6-7):155-158 doi: 10.1016/j.nhtm.2015.11.001.
  • Stellato C, Nassa G, Tarallo R, Giurato G, Ravo M, Rizzo F, Marchese G, Alexandrova E, Cordella A, Baumann M, Nyman TA, Weisz A, Ambrosino C. Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells. Proteomics. 2015 Jun;15(11):1801-7. doi: 10.1002/pmic.201400404.
  • Ravo M, Cordella A, Rinaldi A, Bruno G, Alexandrova E, Saggese P, Nassa G, Giurato G, Tarallo R, Marchese G, Rizzo F, Stellato C, Biancardi R, Troisi J, Di Spiezio Sardo A, Zullo F, Weisz A, Guida M. Small non-coding RNA deregulation in endometrial carcinogenesis. Oncotarget. 2015 Mar 10;6(7):4677-91. doi:10.18632/oncotarget.2911.
  • Hashim A, Rizzo F, Marchese G, Ravo M, Tarallo R, Nassa G, Giurato G, Santamaria G, Cordella A, Cantarella C, Weisz A. RNA sequencing identifies specific PIWI-interacting small non-coding RNA expression patterns in breast cancer. Oncotarget. 2014 Oct 30;5(20):9901-10. PubMed PMID: 25313140.
  • Rizzo F, Hashim A, Marchese G, Ravo M, Tarallo R, Nassa G, Giurato G, Rinaldi A, Cordella A, Persico M, Sulas P, Perra A, Ledda-Columbano GM, Columbano A, Weisz A. Timed regulation of P-element-induced wimpy testis interacting RNA expression during rat liver regeneration. Hepatology. 2014 Sep;60(3):798-806. doi: 10.1002/hep.27267. Epub 2014 Jul 1. PubMed PMID: 24930433. 
  • De Filippo M.R, Rizzo F, Marchese G, Giurato G, Nassa G, Ravo M, Tarallo R, Pironti E, Vecchi M, Crichiutti G, Capizzi G, Verrotti A, Weisz A, Coppola G. Lack of pathogenic mutations in six patients with MMPSI. Epilepsy Res. 2014 Feb;108(2):340-4. doi:10.1016/j.eplepsyres.2013.11.007. Epub 2013 Nov 16. PubMed PMID: 24315024.
  • Scheggi S, Secci ME, Marchese G, De Montis MG, Gambarana C. Influence of palatability on motivation to operate for caloric and non-caloric food in non food-deprived and food-deprived rats. Neuroscience. 2013 Apr 16;236:320-31. doi:10.1016/j.neuroscience.2013.01.027. Epub 2013 Jan 29. PubMed PMID: 23370321.
  • Marchese G, Scheggi S, Secci ME, De Montis MG, Gambarana C. Anti-anhedonic activity of long-term lithium treatment in rats exposed to repeated unavoidable stress. Int J Neuropsychopharmacol. 2013 Aug;16(7):1611-21. doi:10.1017/S1461145712001654. PubMed PMID: 23363811.
  • Grappi S, Marchese G, Secci ME, De Montis MG, Gambarana C, Scheggi S. Morphine sensitization as a model of mania: comparative study of the effects of repeated lithium or carbamazepine administration. Pharmacol Biochem Behav. 2011 Oct;99(4):749-58. doi: 10.1016/j.pbb.2011.06.031. Epub 2011 Jul 1. PubMed PMID:21741986.
  • Scheggi S, Marchese G, Borsini F, Bordi F, De Montis MG. Effects of the5-HT(6) receptor agonist ST 1936 on depression- and anhedonia-like experimental models. Behav Brain Res. 2011 Oct 10;224(1):35-43. doi:10.1016/j.bbr.2011.05.019. Epub 2011 May 27. PubMed PMID: 21645553.
  • Scheggi S, Marchese G, Grappi S, Secci ME, De Montis MG, Gambarana C. Cocaine sensitization models an anhedonia-like condition in rats. Int J Neuropsychopharmacol. 2011 Apr;14(3):333-46. doi: 10.1017/S1461145710000532. Epub 2010 Jun 2. PubMed PMID: 20519061.
  • Danielli B, Scheggi S, Grappi S, Marchese G, De Montis MG, Tagliamonte A, Gambarana C. Modifications in DARPP-32 phosphorylation pattern after repeated palatable food consumption undergo rapid habituation in the nucleus accumbens shell of non-food-deprived rats. J Neurochem. 2010 Jan;112(2):531-41. doi:10.1111/j.1471-4159.2009.06483.x. Epub 2009 Nov 6. PubMed PMID: 19895662.