unisa ITA  unisa ENG


LabMedMolGe - Team

Assunta Sellitto

Assunta Sellitto


e-mail: a.sellitto7@ assellitto@unisa.it

 

Laurea Magistrale in Biologia cum laude, Università degli studi di Salerno (2014).

 

Dottorato di ricerca in Scienze e Tecnologie Biomediche, Università di Roma Tre (in corso)

 

 

Competenze ed attività di ricerca: Biologia cellulare e molecolare, genomica. Applicazione di tecnologie di sequenziamento di nuova generazione (NGS) per lo studio di trascrittomi.

 

Pubblicazioni:

  • Saggese, P., Sellitto, A., Martinez, C., Giurato, G., Nassa, G., Rizzo, F., Tarallo, R. & Scafoglio, C. Metabolic regulation of epigenetic modifications and cell differentiation in cancer. Cancers. 2020 In revision
  • Sellitto A, D’Agostino Y, Alexadrova E, Lamberti J, Pecoraro G, Memoli D, Rocco D, Coviello E, Giurato G, Nassa G, Tarallo R, Weisz A, Rizzo F. Insights into the  role of Estrogen Receptor Beta in Triple Negative Breast Cancer. Cancers. 2020 Jun 5;12(6):1477. doi: 10.3390/cancers12061477.
  • Alexadrova E, Pecoraro G, Sellitto A, Melone V, Ferravante C, Rocco T, Guacci A, Giurato G, Nassa G, Rizzo F, Weisz A, Tarallo R. An overview of candidate therapeutic target genes in ovarian cancer. Cancers. 2020 Jun 4;12(6):1470. doi: 10.3390/cancers12061470.
  • Rizzo F, Vanoli A, Sahnane N, Cerutti R, Trapani D, Rinaldi A, Sellitto A, Ciacci C, Volta U, Villanacci V, Calabrò A, Arpa G, Luinetti O, Paulli M, Solcia E, Di Sabatino A, Sessa F, Weisz A, Furlan D. Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes. Virchows Arch. 2019 Nov 6:10.1007/s00428-019-02675-w. doi: 10.1007/s00428-019-02675-w. Epub ahead of print. PMID: 31696360.
  • Sellitto A, Geles K, D'Agostino Y, Conte M, Alexandrova E, Rocco D, Nassa G, Giurato G, Tarallo R, Weisz A, Rizzo F. Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells. Cells. 2019 Nov 5;8(11):1390. doi: 10.3390/cells8111390. PMID: 31694219; PMCID: PMC6912267.
  • Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A. Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells. Sci Adv. 2019 Feb 6;5(2):eaav5590. doi: 10.1126/sciadv.aav5590. eCollection 2019 Feb. PubMed PMID: 30775443; PubMed Central PMCID: PMC6365116
  • Rizzo F, Rinaldi A, Marchese G, Coviello E, Sellitto A, Cordella A, Giurato G, Nassa G, Ravo M, Tarallo R, Milanesi L, Destro A, Torzilli G, Roncalli M, Di Tommaso L, Weisz A. Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma. Oncotarget. 2016 Jul 13; PubMed PMID: 27429044.
Riassunti pubblicati in atti di convegni nazionali/internazionali:
  • Gigantino V, Salvati A, Alexandrova E, Giurato G, Memoli D, Rizzo F, Sellitto A, Malanga D, Nyman TA, Tarallo R, Weisz A and Nassa G. Pharmacological inhibition of the histone methyltransferase DOT1L as a new epigenetic approach to therapy for endocrine resistant breast cancer. 1st INTERNA-TIONAL AND 32nd Annual Conference of Italian Association of Cell Cultu-res (AICC). 1-2 October 2019, Catanzaro, Italy.
  • Sellitto A, Alexandrova E, Rinaldi A, Panero R., Marchese G, Giurato G, Nassa G, Ravo M, Tarallo R, Rizzo F, Weisz A. Piwi-interacting RNAs (piRNAs) as novel biomarkers in cancer. Proceedings of the National PhD Meeting ABCD. 7-9 April 2016, Salerno, Italy. Pg. 129, Abs. P.97.
  • Rizzo F, Rinaldi A, Coviello E, Sellitto A, Alexandrova E, Cracas D.G.C., Ricciardi L, Di Tommaso L, Roncalli M, Tarallo R, Weisz, A. Identification of specific PIWI-interacting small noncoding RNA (piRNA) expression patterns during hepatocarcinogenesis. Proceedings of the 33rd Joint Meeting of Pathology and Laboratory Medicine SIPMeT ‘Medicina di Precisione, Medicina Traslazionale, Medicina di Laboratorio’. Am J Pathol. 186(suppl): Abst. C38, pg. S18. 2016 (I.F. 4.057).
  • Rinaldi A, Rizzo F, Sellitto A, Memoli D, Giurato G, Trapani D, Sahane N, Furlan D, Giurato G, Weisz A. Involvement of PIWI-interacting RNAs in different molecular and clinicopathological subclasses of colon cancer. Proceedings of BITS 2017 - XIV Annual Meeting of the Bioinformatics Italian Society, July 5-7 2017, Cagliari, Italy. pg. 151-2. 2017.