unisa ITA  unisa ENG


LabMedMolGe - Research

Research activities

The Laboratory of Molecular Medicine and Genomics is involved in many research projects. Following a list of major pubblication:

  • Ferravante C, Memoli, D, Palumbo D, Ciaramella P, Di Loria A, D’Agostino Y, Nassa G, Rizzo F, Tarallo R, Weisz A, Giurato G. HOME-BIO (sHOtgun MEtagenomic analysis of BIOlogical entities): a specific and exhaustive pipeline for handling metagenomic shotgun sequencing data. BMC Bioinformatics. 2020 In revision.
  • Saggese P, Sellitto A, Martinez, C, Giurato G, Nassa G, Rizzo F, Tarallo R, Scafoglio C. Metabolic regulation of epigenetic modifications and cell differentiation in cancer. Cancers. 2020 In revision.
  • Gigantino V, Salvati A, Giurato G, Palumbo D, Strianese O, Rizzo F, Tarallo R, Nyman TA, Weisz A, Nassa G. Identification of Antiestrogen-Bound Estrogen Receptor α Interactomes in Hormone-Responsive Human Breast Cancer Cell Nuclei. Proteomics. 2020 Oct;20(19-20):e2000135. doi: 10.1002/pmic.202000135. Epub 2020 Sep 16. PMID: 32865868.
  • Strianese O, Rizzo F, Ciccarelli M, Galasso G, D'Agostino Y, Salvati A, Del Giudice C, Tesorio P, Rusciano MR. Precision and Personalized Medicine: How Genomic Approach Improves the Management of Cardiovascular and Neurodegenerative Disease. Genes (Basel). 2020 Jul 6;11(7):747. doi: 10.3390/genes11070747. PMID: 32640513; PMCID: PMC7397223.
  • Salvati A, Gigantino V, Nassa G, Mirici Cappa V, Ventola GM, Cracas DGC, Mastrocinque R, Rizzo F, Tarallo R, Weisz A, Giurato G. Global View of Candidate Therapeutic Target Genes in Hormone-Responsive Breast Cancer. Int J Mol Sci. 2020 Jun 6;21(11):4068. doi: 10.3390/ijms21114068. PMID: 32517194; PMCID: PMC7312026.
  • Sellitto A, D’Agostino Y, Alexadrova E, Lamberti J, Pecoraro G, Memoli D, Rocco D, Coviello E, Giurato G, Nassa G, Tarallo R, Weisz A, Rizzo F. Insights into the  role of Estrogen Receptor Beta in Triple Negative Breast Cancer. Cancers. 2020 Jun 5;12(6):1477. doi: 10.3390/cancers12061477. PMID: 32516978.
  • Alexadrova E, Pecoraro G, Sellitto A, Melone V, Ferravante C, Rocco T, Guacci A, Giurato G, Nassa G, Rizzo F, Weisz A, Tarallo R. An overview of candidate therapeutic target genes in ovarian cancer. Cancers. 2020 Jun 4;12(6):1470. doi: 10.3390/cancers12061470. PMID: 32512900.
  • Montico B, Colizzi F, Giurato G, Rizzo A, Salvati A, Baboci L, Benedetti D, Pivetta E, Covre A, Bo MD, Weisz A, Steffan A, Maio M, Sigalotti L, Fratta E. Loss of Spry1 reduces growth of BRAFV600-mutant cutaneous melanoma and improves response to targeted therapy. Cell Death Dis. 2020 May 22;11(5):392. doi: 10.1038/s41419-020-2585-y. PMID: 32444628; PMCID: PMC7244546.
  • Guzzardi, M.A., Ait Ali, L., D’Aurizio, R., Rizzo, F., Saggese, P., Sanguinetti, E., Weisz, A., Pellegrini, M. & Iozzo, P. Fetal cardiac growth is associated with in utero gut colonization. Nutr Metab Cardiovasc Dis. 29: 170-6, 2019. PMID: 30579777.
  • Scalise M, Torella M, Marino F, Ravo M, Giurato G, Vicinanza C, Cianflone E, Mancuso T, Aquila I, Salerno L, Nassa G, Agosti V, De Angelis A, Urbanek K, Veltri P, Mastroroberto P, De Feo M, Viglietto G, Weisz A, Nadal-Ginard B, Ellison GM, Torella D. Atrial Myxomas Arise From Multipotent Cardiac Stem Cells. Eur Heart J. 2020 Apr 24:ehaa156. doi: 10.1093/eurheartj/ehaa156. PMID: 32330934.
  • Alexandrova E, Lamberti J, Saggese P, Pecoraro G, Memoli D, Cappa VM, Ravo M, Iorio R, Tarallo R, Rizzo F, Collina F, Cantile M, Bonito MD, Botti G, Nassa G, Weisz A, Giurato G. Small Non-Coding RNA Profiling Identifies miR-181a-5p as a Mediator of Estrogen Receptor Beta-Induced Inhibition of Cholesterol Biosynthesis in Triple-Negative Breast Cancer. Cells. 2020 Apr 3;9(4):E874. doi: 10.3390/cells9040874. PMID: 32260128.
  • Alexandrova E, Giurato G, Saggese P, Pecoraro G, Lamberti J, Ravo M, Rizzo F, Rocco D, Tarallo R, Nyman TA, Collina F, Cantile M, Di Bonito M, Botti G, Nassa G, Weisz A. Interaction Proteomics Identifies ERbeta Association with Chromatin Repressive Complexes to Inhibit Cholesterol Biosynthesis and Exert An Oncosuppressive Role in Triple-negative Breast Cancer. Mol Cell Proteomics. 2020 Feb;19(2):245-260. doi: 10.1074/mcp.RA119.001817. Epub 2019 Dec 2. PMID: 31792072; PMCID: PMC7000115.
  • Smaldone G, Beneduce G, Incoronato M, Pane K, Franzese M, Coppola L, Cordella A, Parasole R, Ripaldi M, Nassa G, Soricelli A, Vitagliano L, Mirabelli P, Salvatore M. KCTD15 is overexpressed in human childhood B-cell acute lymphoid leukemia. Sci Rep. 2019 Dec 27;9(1):20108. doi: 10.1038/s41598-019-56701-7. PMID: 31882877; PMCID: PMC6934626.
  • Rizzo F, Vanoli A, Sahnane N, Cerutti R, Trapani D, Rinaldi A, Sellitto A, Ciacci C, Volta U, Villanacci V, Calabrò A, Arpa G, Luinetti O, Paulli M, Solcia E, Di Sabatino A, Sessa F, Weisz A, Furlan D. Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes. Virchows Arch. 2019 Nov 6:10.1007/s00428-019-02675-w. doi: 10.1007/s00428-019-02675-w. PMID: 31696360.
  • Sellitto A, Geles K, D'Agostino Y, Conte M, Alexandrova E, Rocco D, Nassa G, Giurato G, Tarallo R, Weisz A, Rizzo F. Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells. Cells. 2019 Nov 5;8(11):1390. doi: 10.3390/cells8111390. PMID: 31694219; PMCID: PMC6912267.
  • Capasso, A., Benigni, A., Capitanio, U., Danesh, F.R., Di Marzo, V., Gesualdo, L., Grandaliano, G., Jaimes. E.A., Malyszko, J., Perazella, M.A., Qian, Q,. Ronco, P., Rosner, M.H., Trepiccione, F., Viggiano, D., Zoccali, C., Capasso G., Weisz, A. & International Conference on Onco-Nephrology Participants. Summary of the International Conference on Onco-Nephrology: An Emerging Field in Medicine. Kidney Int. 96: 555-67, 2019. PMID: 31445584.
  • Salvati A, Gigantino V, Nassa G, Giurato G, Alexandrova E, Rizzo F, Tarallo R, Weisz A. The Histone Methyltransferase DOT1L Is a Functional Component of Estrogen Receptor Alpha Signaling in Ovarian Cancer Cells. Cancers (Basel). 2019 Nov 4;11(11):1720. doi: 10.3390/cancers11111720. PMID: 31689915; PMCID: PMC6895927.
  • Nassa G, Giurato G, Salvati A, Gigantino V, Pecoraro G, Lamberti J, Rizzo F, Nyman TA, Tarallo R, Weisz A. The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei. Sci Data. 2019 Sep 16;6(1):173. doi: 10.1038/s41597-019-0179-2. PubMed PMID: 31527615; PubMed Central PMCID: PMC6746822.
  • Trino S, Zoppoli P, Carella AM, Laurenzana I, Weisz A, Memoli D, Calice G, La Rocca F, Simeon V, Savino L, Del Vecchio L, Musto P, Caivano A, De Luca L. DNA methylation dynamic of bone marrow hematopoietic stem cells after allogeneic transplantation. Stem Cell Res Ther. 2019 May 20;10(1):138. doi: 10.1186/s13287-019-1245-6. PubMed PMID: 31109375; PubMed Central PMCID: PMC6528331.
  • Nassa G, Salvati A, Tarallo R, Gigantino V, Alexandrova E, Memoli D, Sellitto A, Rizzo F, Malanga D, Mirante T, Morelli E, Nees M, Åkerfelt M, Kangaspeska S, Nyman TA, Milanesi L, Giurato G, Weisz A. Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells. Sci Adv. 2019 Feb 6;5(2):eaav5590. doi: 10.1126/sciadv.aav5590. eCollection 2019 Feb. PubMed PMID: 30775443; PubMed Central PMCID: PMC6365116.
  • Ravo M, Cordella A, Saggese P, Rinaldi A, Castaldi MA, Nassa G, Giurato G,Zullo F, Weisz A, Tarallo R, Rizzo F, Guida M. Identification of long non‑coding RNA expression patterns useful for molecular‑based classification of type I endometrial cancers. Oncol Rep. 2019 Feb;41(2):1209-1217. doi: 10.3892/or.2018.6880. Epub 2018 Nov 21. PubMed PMID: 30483802.
  • Ricciardi L, Col JD, Casolari P, Memoli D, Conti V, Vatrella A, Vonakis BM, Papi A, Caramori G, Stellato C. Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients. Int J Chron Obstruct Pulmon Dis. 2018 Oct 12;13:3173-3190. doi: 10.2147/COPD.S166284. eCollection 2018. PubMed PMID: 30349226; PubMed Central PMCID: PMC6190813.
  • Mauro L, Naimo GD, Gelsomino L, Malivindi R, Bruno L, Pellegrino M, Tarallo R, Memoli D, Weisz A, Panno ML, Andò S. Uncoupling effects of estrogen receptor α on LKB1/AMPK interaction upon adiponectin exposure in breast cancer. FASEB J. 2018 Aug;32(8):4343-4355. doi: 10.1096/fj.201701315R. Epub 2018 Mar 7. PubMed PMID: 29513571.
  • Belvedere R, Saggese P, Pessolano E, Memoli D, Bizzarro V, Rizzo F, Parente L,Weisz A, Petrella A. miR-196a Is Able to Restore the Aggressive Phenotype of Annexin A1 Knock-Out in Pancreatic Cancer Cells by CRISPR/Cas9 Genome Editing. Int J Mol Sci. 2018 Jul 6;19(7). pii: E1967. doi: 10.3390/ijms19071967. PubMed PMID: 29986379; PubMed Central PMCID: PMC6073506.
  • Lacunza E, Montanaro MA, Salvati A, Memoli D, Rizzo F, Henning MF, Quiroga IY, Guillou H, Abba MC, Gonzalez-Baro MDR, Weisz A, Pellon-Maison M. Small non-coding RNA landscape is modified by GPAT2 silencing in MDA-MB-231 cells. Oncotarget. 2018 Jun 15;9(46):28141-28154. doi: 10.18632/oncotarget.25582. eCollection 2018 Jun 15. PubMed PMID: 29963267; PubMed Central PMCID: PMC6021339.
  • Giurato G, Nassa G, Salvati A, Alexandrova E, Rizzo F, Nyman TA, Weisz A, Tarallo R. Quantitative mapping of RNA-mediated nuclear Estrogen Receptor β interactome in human breast cancer cells. Scientific Data Mar 2018. Vol. In Press. Pag.1-10 ISSN:2052-4463.
  • Guacci A, Cordella A, Rocco T, Giurato G, Nassa G, Rizzo F, Carlomagno C, Pepe S, Tarallo R, Weisz A. Identification of a novel truncating mutation in PALB2 gene by a multigene sequencing panel for mutational screening of breast cancer risk-associated and related genes. J Clin Lab Anal. 2018 Feb 27. doi: 10.1002/jcla.22418.PubMed PMID: 29484706.
  • Nassa G, Giurato G, Cimmino G, Rizzo F, Ravo M, Salvati A, Nyman TA. Zhu Y, Vesterlund M, Lehtiö J, Golino P, Weisz A, Tarallo R. Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications. Sci Rep. 2018 Jan 11;8(1):498. doi: 10.1038/s41598-017-18985-5. PubMed PMID: 29323256; PubMed Central PMCID: PMC5765118.
  • Tarallo R, Giurato G, Bruno G, Ravo M, Rizzo F, Salvati A, Ricciardi L, Marchese G, Cordella A, Rocco T, Gigantino V, Pierri B, Cimmino G, Milanesi L, Ambrosino C, Nyman TA, Nassa G, Weisz A. The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Genome Biol.2017 Oct 6;18(1):189. doi: 10.1186/s13059-017-1321-0. PubMed PMID: 29017520.
  • Montico B, Lapenta C, Ravo M, Martorelli D, Muraro E, Zeng B, Comaro E, Spada M, Donati S, Santini SM, Tarallo R, Giurato G., Rizzo F, Weisz A, Belardelli F, Dolcetti R, Dal Col J. Exploiting a new strategy to induce immunogenic cell death to improve dendritic cell-based vaccines for lymphoma immunotherapy. Oncoimmunology. 2017 Aug 23.
  • Pistore C, Giannoni E, Colangelo T, Rizzo F, Magnani E, Muccillo L, Giurato G, Mancini M, Rizzo S, Riccardi M, Sahnane N, Del Vescovo V, Kishore K, Mandruzzato M, Macchi F, Pelizzola M, Denti MA, Furlan D, Weisz A, Colantuoni V, Chiarugi P, Bonapace IM. DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells. Oncogene. 2017 Jun 5. doi: 10.1038/onc.2017.159.PubMed PMID: 28581528.
  • Panero R, Rinaldi A, Memoli D, Nassa G, Ravo M, Rizzo F, Tarallo R, Milanesi L, Weisz A, Giurato G. iSmaRT: a toolkit for a comprehensive analysis of small RNA-Seq data. Bioinformatics. 2017 Mar 15;33(6):938-940. doi:10.1093/bioinformatics/btw734. PubMed PMID: 28057684.
  • Porta A, Petrone AM, Morello S, Granata I,Rizzo F, Memoli D, Weisz A, Maresca B. Design and expression of peptides with antimicrobial activity against Salmonella typhimurium. Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12645.
  • Porreca I, D'Angelo F, De Franceschi L, Mattè A, Ceccarelli M, Iolascon A, Zamò A, Russo F, Ravo M, Tarallo R, Scarfò M, Weisz A, De Felice M, Mallardo M, Ambrosino C. Pesticide toxicogenomics across scales: in vitro transcriptome predicts mechanisms and outcomes of exposure in vivo. Sci Rep. 2016 Dec 1;6:38131. doi: 10.1038/srep38131. PubMed PMID: 27905518; PubMed Central PMCID: PMC5131489.
  • Cuomo D, Porreca I, Cobellis G, Tarallo R, Nassa G, Falco G, Nardone A, Rizzo F, Mallardo M, Ambrosino C. Carcinogenic risk and Bisphenol A exposure: A focus on molecular aspects in endoderm derived glands. Mol Cell Endocrinol. 2017 Dec 5;457:20-34. doi: 10.1016/j.mce.2017.01.027. Epub 2017 Jan 19. PubMed PMID:28111205.
  • Lo Piccolo L, Attardi A, Bonaccorso R, Li Greci L, Giurato G, Ingrassia AM, Onorati MC. ISWI ATP-dependent remodeling of nucleoplasmic ω-speckles in the brain of Drosophila melanogaster. J Genet Genomics. 2017 Feb 20;44(2):85-94. doi: 10.1016/j.jgg.2016.12.002. Epub 2016 Dec 22. PubMed PMID: 28209301.
  • D'Arcangelo D, Facchiano F, Nassa G, Stancato A, Antonini A, Rossi S, Senatore C, Cordella M, Tabolacci C, Salvati A, Tarallo R, Weisz A, Facchiano AM, Facchiano A. PDGFR-alpha inhibits melanoma growth via CXCL10/IP-10: a multi-omics approach. Oncotarget. 2016 Nov 22;7(47):77257-77275. doi: 10.18632/oncotarget.12629. PubMed PMID: 27764787; PubMed Central PMCID: PMC5363585.
  • Fiume G, Scialdone A, Rizzo F, De Filippo MR, Laudanna C, Albano F, Golino G, Vecchio E, Pontoriero M, Mimmi S, Ceglia S, Pisano A, Iaccino E, Palmieri C, Paduano S, Viglietto G, Weisz A, Scala G, Quinto I. IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells. Int J Mol Sci. 2016 Nov 7;17(11). pii: E1848
  • Pazienza V, Panebianco C, Rappa F, Memoli D, Borghesan M, Cannito S, Oji A, Mazza G, Tamburrino D, Fusai G, Barone R, Bolasco G, Villarroya F, Villarroya J, Hatsuzawa K, Cappello F, Tarallo R, Nakanishi T, Vinciguerra M. Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis. Epigenetics Chromatin. 2016 Oct 25;9:45. eCollection 2016. PubMed PMID: 27800025; PubMed Central PMCID: PMC5078890.
  • Santangelo L, Giurato G*, Cicchini C, Montaldo C, Mancone C, Tarallo R, Battistelli C, Alonzi T, Weisz A, Tripodi M. The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting. Cell Rep. 2016 Oct 11;17(3):799-808. doi: 10.1016/j.celrep.2016.09.031. PubMed PMID: 27732855.*Co-first author.
  • Caporali S, Alvino E, Lacal PM, Levati L, Giurato G, Memoli D, Caprini E, Antonini Cappellini GC, D'Atri S. Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor. Int J Oncol. 2016 Sep;49(3):1164-74. doi: 10.3892/ijo.2016.3594. Epub 2016 Jun 30. PubMed PMID: 27572607.
  • De Palma R, Cirillo P, Ciccarelli G, Barra G, Conte S, Pellegrino G, Pasquale G, Nassa G, Pacifico F, Leonardi A, Insabato L, Calì G, Golino P, Cimmino G. Expression of functional tissue factor in activated T-lymphocytes in vitro and in vivo: A possible contribution of immunity to thrombosis? Int J Cardiol. 2016 Sep 1;218:188-195. doi: 10.1016/j.ijcard.2016.04.177. Epub 2016 May 3. PubMed PMID: 27236113.
  • Rizzo F, Rinaldi A, Marchese G, Coviello E, Sellitto A, Cordella A, Giurato G, Nassa G, Ravo M, Tarallo R, Milanesi L, Destro A, Torzilli G, Roncalli M, Di Tommaso L, Weisz A. Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma. Oncotarget. 2016 Aug 23;7(34):54650-54661. doi: 10.18632/oncotarget.10567. PubMed PMID: 27429044; PubMed Central PMCID: PMC5342370.
  • Marchese G, Rizzo F, Guacci A, Weisz A, Coppola G. Kleefstra-variant syndrome with heterozygous mutations in EHMT1 and KCNQ2 genes: a case report. Neurol Sci. 2016 May;37(5):829-31. doi: 10.1007/s10072-016-2482-4. 
  • Rizzo F, Coffman JA, Arnone MI. An Elk transcription factor is required for Runx-dependent survival signaling in the sea urchin embryo. Dev Biol. 2016 Aug 1;416(1):173-186. doi: 10.1016/j.ydbio.2016.05.026. Epub 2016 May 24.
  • Alexandrova E, Nassa G, Corleone G, Buzdin A, Aliper AM, Terekhanova N, Shepelin D, Zhavoronkov A, Tamm M, Milanesi L, Miglino N, Weisz A, Borger P. Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cells. Oncotarget. 2016 May 3;7(18):25150-61. doi: 10.18632/oncotarget.7209. PubMed PMID: 26863634; PubMed Central PMCID: PMC5039037.
  • Catalano S, Campana A, Giordano C, Győrffy B, Tarallo R, Rinaldi A, Bruno G, Ferraro A, Romeo F, Lanzino M, Naro F, Bonofiglio D, Andò S, Barone I. Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy. Clin Cancer Res. 2016 May 1;22(9):2271-82. doi: 10.1158/1078-0432.CCR-15-1900. Epub 2015 Dec 14. PubMed PMID: 26667489.
  • Rizzo F, Ambrosino P, Guacci A, Chetta M, Marchese G, Rocco T, Soldovieri MV, Manocchio L, Mosca I, Casara G, Vecchi M, Taglialatela M, Coppola G, Weisz A. Characterization of two de novoKCNT1 mutations in children with malignant migrating partial seizures in infancy. Mol Cell Neurosci. 2016 Apr;72:54-63. doi:10.1016/j.mcn.2016.01.004. 
  • Alexandrova E, Miglino N, Hashim A, Nassa G, Stellato C, Tamm M, Baty F, Brutsche M, Weisz A, Borger P. Small RNA profiling reveals deregulated phosphatase and tensin homolog (PTEN)/phosphoinositide 3-kinase (PI3K)/Akt pathway in bronchial smooth muscle cells from asthmatic patients. J Allergy Clin Immunol. 2016 Jan;137(1):58-67. doi: 10.1016/j.jaci.2015.05.031. Epub 2015 Jul 3. PubMed PMID: 26148798
  • Guacci A, Chetta M, Rizzo F, Marchese G, De Filippo MR, Giurato G, Nassa G, Ravo M, Tarallo R, Rocco T, Operto FF, Weisz A, Coppola G. Phenytoin neurotoxicity in a child carrying new STXBP1 and CYP2C9 gene mutations. Seizure. 2016 Jan;34:26-8. doi: 10.1016/j.seizure.2015.11.004. Epub 2015 Nov 21. PubMed PMID: 26658169.
  • De Rosa MC, Caputo M, Zirpoli H, Rescigno T, Tarallo R, Giurato G, Weisz A, Torino G, Tecce MF. Identification of Genes Selectively Regulated in Human Hepatoma Cells by Treatment With Dyslipidemic Sera and PUFAs. J Cell Physiol. 2015 Sep;230(9):2059-66. doi: 10.1002/jcp.24932. PubMed PMID: 25639214.
  • Chetta M, Guacci A, Rizzo F,  Operto FF, Weisz A, and Coppola G.  Infantile spasms in early-onset Niemann-Pick disease with a novel compound heterozygous mutations in SMPD1 gene. New Horizons in Translational Medicine. 2015 Sep; 2(6-7):155-158 doi: 10.1016/j.nhtm.2015.11.001.
  • Stellato C, Porreca I, Cuomo D, Tarallo R, Nassa G, Ambrosino C. The "busy life" of unliganded estrogen receptors. Proteomics. 2016 Jan;16(2):288-300. doi: 10.1002/pmic.201500261. Epub 2015 Dec 17. Review. PubMed PMID: 26508451..
  • Pibiri M, Sulas P, Leoni VP, Perra A, Kowalik MA, Cordella A, Saggese P, Nassa G, Ravo M. Global gene expression profile of normal and regenerating liver in young and old mice. Age (Dordr). 2015 Jun;37(3):9796. doi: 10.1007/s11357-015-9796-7. Epub 2015 Jun 3. PubMed PMID: 26036689; PubMed Central PMCID: PMC4451458.
  • Cimmino G, Tarallo R, Nassa G, De Filippo MR, Giurato G, Ravo M, Rizzo F, Conte S, Pellegrino G, Cirillo P, Calabro P, Öhman T, Nyman TA, Weisz A, Golino P. Activating stimuli induce platelet microRNA modulation and proteome reorganisation. Thromb Haemost. 2015 Jul;114(1):96-108. doi: 10.1160/TH14-09-0726. Epub 2015 Apr 23. PubMed PMID: 25903651.
  • Dago DN, Scafoglio C, Rinaldi A, Memoli D, Giurato G, Nassa G, Ravo M, Rizzo F, Tarallo R, Weisz A. Estrogen receptor beta impacts hormone-induced alternative mRNA splicing in breast cancer cells. BMC Genomics. 2015 May 9;16:367. doi: 10.1186/s12864-015-1541-1. PubMed PMID: 25956916; PubMed Central PMCID: PMC4424892.
  • Stellato C, Nassa G, Tarallo R, Giurato G, Ravo M, Rizzo F, Marchese G, Alexandrova E, Cordella A, Baumann M, Nyman TA, Weisz A, Ambrosino C. Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells. Proteomics. 2015 Jun;15(11):1801-7. doi: 10.1002/pmic.201400404. Epub 2015 Mar 18. PubMed PMID: 25604459.
  • Ravo M, Cordella A, Rinaldi A, Bruno G, Alexandrova E, Saggese P, Nassa G, Giurato G, Tarallo R, Marchese G, Rizzo F, Stellato C, Biancardi R, Troisi J, Di Spiezio Sardo A, Zullo F, Weisz A, Guida M. Small non-coding RNA deregulation in endometrial carcinogenesis. Oncotarget. 2015 Mar 10;6(7):4677-91. PubMed PMID: 25686835; PubMed Central PMCID: PMC4467107.
  • Caputo M, Zirpoli H, De Rosa MC, Rescigno T, Chiadini F, Scaglione A, Stellato C, Giurato G, Weisz A, Tecce MF, Bisceglia B. Effect of low frequency (LF) electric fields on gene expression of a bone human cell line. Electromagn Biol Med. 2014 Dec;33(4):289-95. doi: 10.3109/15368378.2013.822387. Epub 2013 Aug 26. PubMed PMID: 23977831.
  • Misaggi R, Di Sanzo M, Cosentino C, Bond HM, Scumaci D, Romeo F, Stellato C, Giurato G, Weisz A, Quaresima B, Barni T, Amato F, Viglietto G, Morrone G, Cuda G, Faniello MC, Costanzo F. Identification of H ferritin-dependent and independent genes in K562 differentiating cells by targeted gene silencing and expression profiling. Gene. 2014 Feb 10;535(2):327-35. doi: 10.1016/j.gene.2013.10.067. Epub 2013 Nov 14. PubMed PMID: 24239552.
  • Hashim A, Rizzo F, Marchese G, Ravo M, Tarallo R, Nassa , Giurato G, Santamaria G, Cordella A, Cantarella C, Weisz A. RNA sequencing identifies specific PIWI-interacting small non-coding RNA expression patterns in breast cancer. Oncotarget. 2014 Oct 30;5(20):9901-10. PubMed PMID: 25313140; PubMed Central PMCID: PMC4259446.
  • Rizzo F, Hashim A, Marchese G, Ravo M, Tarallo R, Nassa G, Giurato G, Rinaldi A, Cordella A, Persico M, Sulas P, Perra A, Ledda-Columbano GM, Columbano A, Weisz A. Timed regulation of P-element-induced wimpy testis-interacting RNA expression during rat liver regeneration. Hepatology. 2014 Sep;60(3):798-806. doi: 10.1002/hep.27267. Epub 2014 Jul 1. PubMed PMID: 24930433.
  • Nassa G, Tarallo R, Giurato G, De Filippo MR, Ravo M, Rizzo F, Stellato C,Ambrosino C, Baumann M, Lietzèn N, Nyman TA, Weisz A. Post-transcriptionalregulation of human breast cancer cell proteome by unliganded estrogen receptor β via microRNAs. Mol Cell Proteomics. 2014 Apr;13(4):1076-90. doi:10.1074/mcp.M113.030403. Epub 2014 Feb 13. PubMed PMID: 24525454; PubMed Central PMCID: PMC3977185.
  • Strazzullo M, Gasparrini B, Neglia G, Balestrieri ML, Francioso R, Rossetti C, Nassa G, De Filippo MR, Weisz A, Di Francesco S, Vecchio D, D'Esposito M, D'Occhio MJ, Zicarelli L, Campanile G. Global transcriptome profiles of Italian Mediterranean buffalo embryos with normal and retarded growth. PLoS One. 2014 Feb 28;9(2):e90027. doi: 10.1371/journal.pone.0090027. eCollection 2014. PubMed PMID: 24587197; PubMed Central PMCID: PMC3938533.
  • Casale FP, Giurato G, Nassa G, Armond JW, Oates CJ, Corá D, Gamba A, Mukherjee S, Weisz A, Nicodemi M. Single-cell states in the estrogen response of breast cancer cell lines. PLoS One. 2014 Feb 25;9(2):e88485. doi: 10.1371/journal.pone.0088485. eCollection 2014. PubMed PMID: 24586334; PubMed Central PMCID: PMC3934861
  • Giurato G, De Filippo M.R, Rinaldi A, Hashim A, Nassa G, Ravo M, Rizzo F, Tarallo R, Weisz A. iMir: An Integrated pipeline for high-throughput analysis of small non-coding data obtained by miRNA-Seq. BMC Bioinformatics. 2013 Dec 13;14:362. doi: 10.1186/1471-2105-14-362. PubMed PMID: 24330401; PubMed Central PMCID: PMC3878829.
  • De Filippo M.R, Rizzo F, Marchese G, Giurato G, Nassa G, Ravo M, Tarallo R, Pironti E, Vecchi M, Crichiutti G, Capizzi G, Verrotti A, Weisz A, Coppola G. Lack of pathogenic mutations in six patients with MMPSI. Epilepsy Res. 2014 Feb;108(2):340-4. doi:10.1016/j.eplepsyres.2013.11.007. Epub 2013 Nov 16. PubMed PMID: 24315024.
  • Ambrosino C, Tarallo R, Nassa G, Cirillo F, Weisz. A new insights on estrogen receptor actions in hormone-responsive breast cancer cells by interaction proteomics. Cell and Molecular biology of breast cancer: Heide Shutter editor, Humana press. Chapter 8, DOI 10.1007/978-1-62703-634-4_8, 2013
  • Cirillo F, Nassa G, Tarallo R, Stellato C, De Filippo MR, Ambrosino C, Baumann M, Nyman TA, Weisz A. Molecular mechanisms of selective estrogen receptor modulator activity in human breast cancer cells: identification of novel nuclear cofactors of antiestrogen-ERα complexes by interaction proteomics. J Proteome Res. 2013 Jan 4;12(1):421-31. doi: 10.1021/pr300753u. Epub 2012 Nov 30. PubMed PMID: 23170835.
  • Ferraro L, Ravo M, Nassa G, Tarallo R, De Filippo MR, Giurato G, Cirillo F, Stellato C, Silvestro S, Cantarella C, Rizzo F, Cimino D, Friard O, Biglia N, De Bortoli M, Cicatiello L, Nola E, Weisz A. Effects of oestrogen on microRNA expression in hormone-responsive breast cancer cells. Horm Cancer. 2012 Jun;3(3):65-78. doi: 10.1007/s12672-012-0102-1. PubMed PMID: 22274890
  • Paris O, Ferraro L, Grober OM, Ravo M, De Filippo MR, Giurato G, Nassa G, Tarallo R, Cantarella C, Rizzo F, Di Benedetto A, Mottolese M, Benes V, Ambrosino C, Nola E, Weisz A. Direct regulation of microRNA biogenesis and expression by estrogen receptor beta in hormone-responsive breast cancer. Oncogene. 2012 Sep 20;31(38):4196-206. doi: 10.1038/onc.2011.583. Epub 2012 Jan 9. PubMed PMID: 22231442
  • Grober OM, Mutarelli M, Giurato G, Ravo M, Cicatiello L, De Filippo MR, Ferraro L, Nassa G, Papa MF, Paris O, Tarallo R, Luo S, Schroth GP, Benes V, Weisz A. Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation. BMC Genomics. 2011 Jan 14;12:36. doi: 10.1186/1471-2164-12-36. PubMed PMID: 21235772; PubMed Central PMCID: PMC3025958.